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Browse health-related classes, events and support groups offered by Gundersen Health System.
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Healthy Living with Diabetes
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Healthy Living with Chronic Pain
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Gundersen Palmer Lutheran Grief Support Group
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Free eight-week grief support group in West Union, Iowa, offered in the spring and fall
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Grief Education Support Group
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news
Eight graduates complete Project SEARCH internships
On May 24, eight students representing five Coulee Region schools were celebrated for their hard work and accomplishments at the 2024 Project SEARCH graduation ceremony at Gundersen Health System. ...
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Gundersen Renal Dialysis Center Viroqua
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Whether you have a new kidney problem or are actively managing kidney disease, you want the best treatment and specialists. Consult your healthcare provider regarding outpatient or home dialysis options.
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Gundersen W. R. Yutuc Renal Dialysis Center Onalaska
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Whether you have a new kidney problem or are actively managing kidney disease, you want the best treatment and specialists. Consult your healthcare provider regarding outpatient or home dialysis options.
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Gundersen Renal Dialysis Center Tomah
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Whether you have a new kidney problem or are actively managing kidney disease, you want the best treatment and specialists. Consult your healthcare provider regarding outpatient or home dialysis options.
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Gundersen Renal Dialysis Center Prairie du Chien
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Whether you have a new kidney problem or are actively managing kidney disease, you want the best treatment and specialists. Consult your healthcare provider regarding outpatient or home dialysis options.
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Gundersen Renal Dialysis Center La Crosse
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Gundersen Lutheran Medical Center in La Crosse provides inpatient dialysis service 24/7. Home dialysis patients and outpatients with acute renal failure also receive services at the La Crosse location. Consult your healthcare provider regarding outpatient or home dialysis options.
ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells
Paige Dausinas
ARID3A and ARID3B are paralogs from the AT-Rich interactive Domain (ARID) family. ARID3A and ARID3B associate to regulate genes in B-cells and cancer. We were the first to demonstrate that ARID3B regulates stem cell genes and promotes the cancer stem cell phenotype. Importantly, different knockout phenotypes in mice and distinct patterns of expression in adult animals suggests that ARID3A and ARID3B may have unique functions. In addition, high levels of ARID3B but not ARID3A induce cell death....
Can Stemness and Chemoresistance Be Therapeutically Targeted via Signaling Pathways in Ovarian Cancer?
Lynn Roy
Ovarian cancer is the most lethal gynecological malignancy. Poor overall survival, particularly for patients with high grade serous (HGS) ovarian cancer, is often attributed to late stage at diagnosis and relapse following chemotherapy. HGS ovarian cancer is a heterogenous disease in that few genes are consistently mutated between patients. Additionally, HGS ovarian cancer is characterized by high genomic instability. For these reasons, personalized approaches may be necessary for effective...
Evidence of a Protein-Coding Gene Antisense to the U<sub>L</sub>5 Gene in Bovine Herpesvirus I
Victoria A Jefferson
Bovine herpesvirus type 1 (BoHV-1) is an important agricultural pathogen that infects cattle and other ruminants worldwide. Though it was first sequenced and annotated over twenty years ago, the Cooper strain, used in this study, was sequenced as recently as 2012 and is currently said to encode 72 unique proteins. However, tandem mass spectrometry has identified several peptides produced during active infection that align with the BoHV-1 genome in unannotated regions. One of these abundant...
Gemcitabine combination therapies induce apoptosis in uterine carcinosarcoma patient-derived organoids
Matías J Dahl
Uterine carcinosarcoma (UCS) is a rare but aggressive endometrial cancer. Survival outcomes for women diagnosed with UCS remain poor with lower survival than those of endometrioid or high-grade serous uterine cancers. The histopathological hallmark of carcinosarcoma is the presence of both sarcomatous and carcinomatous elements. The survival rates for UCS have not improved for over 40 years; therefore, there is a profound need to identify new treatments. To investigate novel chemotherapy...
IKKα-Mediated Noncanonical NF-κB Signaling Is Required To Support Murine Gammaherpesvirus 68 Latency <em>In Vivo</em>
Brandon Cieniewicz
Noncanonical NF-κB signaling is activated in B cells via the tumor necrosis factor (TNF) receptor superfamily members CD40, lymphotoxin β receptor (LTβR), and B-cell-activating factor receptor (BAFF-R). The noncanonical pathway is required at multiple stages of B cell maturation and differentiation, including the germinal center reaction. However, the role of this pathway in gammaherpesvirus latency is not well understood. Murine gammaherpesvirus 68 (MHV68) is a genetically tractable system used...