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Sterile Processing Technician Training Program
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Sterile processing technicians, also called central service technicians, play a critical role in patient care, safety and infection prevention in our hospitals and clinics. Now you can begin a meaningful career as a sterile processing technician at Gundersen and receive free training to become a sterile processing technician.
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Gundersen Boscobel DAISY Award
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Our nurses are remarkable. The DAISY Award is your opportunity to honor them for the difference they make.
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Classes & Events
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Browse health-related classes, events and support groups offered by Gundersen Health System.
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Bariatric Surgery Pre-surgery Q&A Panel Registration
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Register for the Q&A panel using the form below.
news
Gundersen Tri-County christens new hospital with ribbon-cutting ceremony
Gundersen Health System is celebrating another milestone in its pledge to provide care close to home with the dedication of the new Gundersen Tri-County Hospital in Whitehall. ...
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Emplify Health invests in local care, acquires Mondovi clinic
Emplify Health has acquired the clinic in Mondovi from HSHS/Prevea Health and expects to open for patient care in the coming months. ...
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Gundersen Pharmacy – St. Elizabeth’s Wabasha
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Fill your prescriptions quickly while visiting our on-site pharmacy at Gundersen St. Elizabeth's. We offer Saturday hours, a complete line of home health aids, free mail delivery of your prescriptions and friendly service by our experienced pharmacists.
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Gundersen Pharmacy – Holmen
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With extended evening and Saturday hours, we make it easy to get your prescriptions filled at our pharmacy in Holmen. We offer free home and mail delivery, a full line of home health aids, and friendly service from experienced pharmacists who are ready to help.
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Gundersen Boscobel Clinic
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At Gundersen Boscobel Clinic, we bring convenient, personalized, patient-centered primary care to patients of all ages.
event
Life After Bariatric Surgery: Learn from Those Who've Been There
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ARID3A and ARID3B induce stem promoting pathways in ovarian cancer cells

Paige Dausinas
ARID3A and ARID3B are paralogs from the AT-Rich interactive Domain (ARID) family. ARID3A and ARID3B associate to regulate genes in B-cells and cancer. We were the first to demonstrate that ARID3B regulates stem cell genes and promotes the cancer stem cell phenotype. Importantly, different knockout phenotypes in mice and distinct patterns of expression in adult animals suggests that ARID3A and ARID3B may have unique functions. In addition, high levels of ARID3B but not ARID3A induce cell death....

Can Stemness and Chemoresistance Be Therapeutically Targeted via Signaling Pathways in Ovarian Cancer?

Lynn Roy
Ovarian cancer is the most lethal gynecological malignancy. Poor overall survival, particularly for patients with high grade serous (HGS) ovarian cancer, is often attributed to late stage at diagnosis and relapse following chemotherapy. HGS ovarian cancer is a heterogenous disease in that few genes are consistently mutated between patients. Additionally, HGS ovarian cancer is characterized by high genomic instability. For these reasons, personalized approaches may be necessary for effective...

Evidence of a Protein-Coding Gene Antisense to the U<sub>L</sub>5 Gene in Bovine Herpesvirus I

Victoria A Jefferson
Bovine herpesvirus type 1 (BoHV-1) is an important agricultural pathogen that infects cattle and other ruminants worldwide. Though it was first sequenced and annotated over twenty years ago, the Cooper strain, used in this study, was sequenced as recently as 2012 and is currently said to encode 72 unique proteins. However, tandem mass spectrometry has identified several peptides produced during active infection that align with the BoHV-1 genome in unannotated regions. One of these abundant...

Gemcitabine combination therapies induce apoptosis in uterine carcinosarcoma patient-derived organoids

Matías J Dahl
Uterine carcinosarcoma (UCS) is a rare but aggressive endometrial cancer. Survival outcomes for women diagnosed with UCS remain poor with lower survival than those of endometrioid or high-grade serous uterine cancers. The histopathological hallmark of carcinosarcoma is the presence of both sarcomatous and carcinomatous elements. The survival rates for UCS have not improved for over 40 years; therefore, there is a profound need to identify new treatments. To investigate novel chemotherapy...

IKKα-Mediated Noncanonical NF-κB Signaling Is Required To Support Murine Gammaherpesvirus 68 Latency <em>In Vivo</em>

Brandon Cieniewicz
Noncanonical NF-κB signaling is activated in B cells via the tumor necrosis factor (TNF) receptor superfamily members CD40, lymphotoxin β receptor (LTβR), and B-cell-activating factor receptor (BAFF-R). The noncanonical pathway is required at multiple stages of B cell maturation and differentiation, including the germinal center reaction. However, the role of this pathway in gammaherpesvirus latency is not well understood. Murine gammaherpesvirus 68 (MHV68) is a genetically tractable system used...

Lytic Replication and Reactivation from B Cells Is Not Required for Establishing or Maintaining Gammaherpesvirus Latency <em>In Vivo</em>

Arundhati Gupta
Gammaherpesviruses (GHVs) are lymphotropic tumor viruses with a biphasic infectious cycle. Lytic replication at the primary site of infection is necessary for GHVs to spread throughout the host and establish latency in distal sites. Dissemination is mediated by infected B cells that traffic hematogenously from draining lymph nodes to peripheral lymphoid organs, such as the spleen. B cells serve as the major reservoir for viral latency, and it is hypothesized that periodic reactivation from...

1900 South Ave.
La Crosse, WI 54601

(608) 782-7300

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