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Showing 16 of 4500 results

Emergence and onward transmission of a SARS-CoV-2 E484K variant among household contacts of a bamlanivimab-treated patient

Arick P Sabin
The implementation of monoclonal antibody therapeutics during the COVID-19 pandemic altered the selective pressures encountered by SARS-CoV-2, raising the possibility of selection for resistant variants. Within-host viral evolution was reported in treated immunocompromised individuals but whether this signifies a real risk of onward transmission is unclear. We used a regional SARS-CoV-2 sequencing program to monitor lineages with clinically relevant variants in identified patients, which...

Emergence and onward transmission of a SARS-CoV-2 E484K variant among household contacts of a bamlanivimab-treated patient

Arick P Sabin
The implementation of monoclonal antibody therapeutics during the COVID-19 pandemic altered the selective pressures encountered by SARS-CoV-2, raising the possibility of selection for resistant variants. Within-host viral evolution was reported in treated immunocompromised individuals but whether this signifies a real risk of onward transmission is unclear. We used a regional SARS-CoV-2 sequencing program to monitor lineages with clinically relevant variants in identified patients, which...

Optimized infection control practices augment the robust protective effect of vaccination for ESRD patients during a hemodialysis facility SARS-CoV-2 outbreak

Megan E Meller
CONCLUSIONS: Prompt recognition of an infection cluster and rapid intervention efforts successfully ended the outbreak. Alongside consistent adherence to core infection prevention measures, vaccination was highly effective in reducing disease incidence and morbidity in this vulnerable population.

Optimized infection control practices augment the robust protective effect of vaccination for ESRD patients during a hemodialysis facility SARS-CoV-2 outbreak

Megan E Meller
CONCLUSIONS: Prompt recognition of an infection cluster and rapid intervention efforts successfully ended the outbreak. Alongside consistent adherence to core infection prevention measures, vaccination was highly effective in reducing disease incidence and morbidity in this vulnerable population.

Outbreak or pseudo-outbreak? Integrating SARS-CoV-2 sequencing to validate infection control practices in a dialysis facility

Bridget L Pfaff
CONCLUSIONS: With high community prevalence, epidemiological data alone is insufficient to deem a case cluster an outbreak. Cluster evaluation with genomic data, when available with a short turn-around time, can play an important role in infection prevention and control response programs.

Pan-cancer distribution of cleaved cell-surface amphiregulin, the target of the GMF-1A3 antibody drug conjugate

Kristopher A Lofgren
Amphiregulin is a transmembrane protein which, when cleaved by the TACE/ADAM17 protease, releases a soluble epidermal growth factor receptor ligand domain that promotes proliferation of normal and malignant cells. We previously described a rabbit monoclonal antibody, GMF-1A3, that selectively recognizes the cell-associated cleaved amphiregulin epitope. Antibody-drug conjugates had anti-tumor activity against human breast cancer xenografts. Several tumor types express amphiregulin, but evidence...
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Family Medicine Sub-Internships
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Use our form below to apply for our Family Medicine M4 elective rotation, offered July through December each year.
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General Surgery Sub-Internship Application
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As a medical student, you’ll serve an integral part of Gundersen’s surgical team alongside our General Surgery residents and faculty.
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Non UW-L Physician Assistant (PA) Application
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We welcome PA students at the University of Wisconsin-La Crosse (UW-L) and other institutions for clinical placement each year.

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Cosmetic Promotions
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Save 25% on sunscreen products in May!
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Gundersen Visitor Guidelines
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Masking is optional at all of our locations. If you’re ill and need our care, please mask to protect our patients, visitors and your care team. Review our guidelines if you’re planning to visit our hospitals or clinics.
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Gundersen La Crosse Campus
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Our roots run deep in La Crosse and we're proud to still call it home. Our La Crosse Campus is where our patients in Wisconsin, Minnesota and Iowa visit for the life-saving, routine and preventative care they need, along with the right amount of love we're proud to deliver.
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MyChart Arrivals
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When you arrive in the waiting room, you can use MyChart to let us know you're here. 
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Two systems, one vision
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Gundersen Health System and Bellin Health Systems deliver superior primary and specialized care in Wisconsin, Minnesota, Iowa and Upper Michigan. This year, they united to deliver world-class medical care that strengthens patient and community health. Separately, Gundersen and Bellin Health have cared for their communities for more than a century. Our path forward together means we’ll be here for another 100 years and beyond.

1900 South Ave.
La Crosse, WI 54601

(608) 782-7300
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