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Multidisciplinary Research

The multi-specialty research group supports research in:


  • The Chronicle Study: A Longitudinal Prospective Observational Study of the Characteristics, Treatment Patterns and Health Outcomes of Individuals with Severe Asthma in the United States.

  • RAPID: Registry of Asthma Patients Initiating DUPIXENT®


  • The MIST Trial: Minimally Invasive Coronary Surgery Compared to Sternotomy Coronary Artery Bypass Grafting


  • No studies available at this time.


  • No studies available at this time.

Interventional Radiology

  • The C-TRACT Trial: Chronic venous thrombosis: relief with adjunctive catheter-directed therapy
  • BEST Registry: Prospective multicenter registry evaluating the real world therapeutic strategies, clinical outcomes, and costs associated with patients presenting with critical limb ischemia.
  • CLOUT: ClotTriever Outcomes Registry

Internal Medicine

  • ACTIV-1 IM: Immune Modulators for Treating COVID-19. A master protocol designed to evaluate multiple investigational agents for the treatment of moderately or severely ill patients infected with severe acute respiratory coronavirus 2 (SARS-CoV-2).


  • Crest-2: Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (Crest-2) Protocol
  • CREST-H: Carotid Revascularization and Medical Management for Asymptomatic Carotid stenosis - Hemodynamics
  • Sleep SMART: Sleep for Stroke Management and Recovery Trial


  • Children’s Health in the Heartland Study (CHHS): This study will measure biological and epigenetic biomarkers from mother-baby pairs to assess the extent of prenatal GBH (glyphosphate-based herbicide) pesticide exposures in pregnant Midwestern women and associations with adverse reproductive outcomes and the developing child. Additionally, epigenetic biomarkers may also be measured to further assess paternal exposure effects.


  • No studies available at this time.


  • Active Spacer: A Prospective Post-market Study to determine the effect of the Active Spacer on soft tissue balancing and patient reported outcomes measures (PROMs) in robotic-assisted total knee arthroplasty.
  • Restrata Study: Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix with Lyophilized Acellular Fish Skin in Treating Diabetic Foot Ulcers (DFU) and with Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)


  • No studies available at this time.


  • 133-CL-01: Vectra Involved Informed Decision Outcome Study (VIVID): A prospective randomized controlled trial evaluating the effect of guided care with Vectra compared to treatment as usual in patients with rheumatoid arthritis


  • No studies available at this time.

If you are interested in getting additional information on a research study, please contact:

Jonean Thorsen, RN
(608) 775-7001 or (800) 362-9567, ext. 57001
[email protected]

Christine Roraff, RN
(608) 775-7001 or (800) 362-9567, ext. 57001
[email protected]

Industry Sponsored Research

Clinical research at Gundersen vital to FDA approval process

For several years, Gundersen Health System has joined with other major medical centers to conduct research trials essential in determining the safety and effectiveness of new medicines and technologies. Many Gundersen departments have participated in these trials—among them Cardiology, Endocrinology, Family Practice, Internal Medicine, Neurology, Pediatrics, Pulmonary, Rheumatology and Urology.

The Clinical Research department is self-supporting. All or most clinical trial-related costs such as clinic visits, laboratory tests, study drugs or devices and patient stipends for time and travel expenses are paid for with funds provided by the sponsoring pharmaceutical or medical device companies.

All patient participation in clinical trials is voluntary. Some patients volunteer hoping to benefit from a promising new medication or treatment that is not yet approved by the Food and Drug Administration. Most patients also are motivated by a desire to help others by providing information that could increase understanding and lead to better treatments.

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1900 South Ave.
La Crosse, WI 54601

(608) 782-7300

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