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Non-Cancer Clinical Trials

The multi-specialty research group supports research in:


  • No studies at this time


  • Ischemia: International Study of Comparative Health Effectiveness with Medical and Invasive Approaches
  • Artemis: Affordability and Real-World Anti Platelet Treatment Effectiveness after Myocardial Infarction Study (closed to enrollment)
  • CardioMEMS: Heart Failure System Post Approval Study
  • MPP PMS: Multipoint Pacing (MPP) Post Market Study
  • PRIME-HF: Predischarge Initiation of Ivabradine in the Management of Heart Failure (PRIME-HF)


  • PERL: Preventing Early Renal Loss in Diabetes (Closed to enrollment)

Interventional Radiology

  • Attract: Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis (Closed to enrollment)
  • BEST Trial: Best Endovascular vs Best Surgical Therapy in Patients With Critical Limb Ischemia


  • No studies at this time


  • Crest-2: Carotid Revascularization and Medical Management for Aysymptomatic Carotid Stenosis Trial (Crest-2) Protocol
  • IDEAS: Imaging Dementia- Evidence for Amyloid Scanning Study: A Coverage Evidence Development Longitudinal Cohort Study
  • Respect: Randomized, double-blind, evaluation in secondary stroke prevention comparing the Efficacy and safety of the oral Thrombin inhibitor dabigatran etexilate versus acetylsalicylic acid in patients with Embolic Stroke of Undetermined Course (RESPECT ESUS)
  • SMART study: A Prospective, Multicenter Study Assessing the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil


  • Glaucoma: A Prospective, Randomized, Multi-Center, Open-Label Trial Comparing a Novel Goniotomy Procedure and an Ab Interno Trabecular Bypass Device in the Treatment of Mild to Moderate Glaucoma in Patients Undergoing Cataract Extraction


  • NAVIGATE: Clinical Evaluation of superDimension Navigation System for Electromagnetic Navigation Bronchoscopy (closed to enrollment)
  • Percepta: Prospective Registry to Evaluate Percepta Bronchial Genomic Classifier Patient Data: The PERCEPTA Registry


  • AWARE: Comparative and Pragmatic Study of Golimumab Intravenous (IV) (Simponi Aria) Versus Infliximab (Remicade) in Rheumatoid Arthritis (AWARE)
  • Axial Spondyloarthritis (AS0006): Phase 3, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy and Safety of Certilozumab Pegol in Subjects with Active Axial Spondyloarthritis (AxSpa) without X-Ray Evidence of Ankylosing Spondylitis (AS) and Objective Signs of Inflammation
  • Lupus Nephritis (HGS1066-C1121): A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Belimumab plus Standard of Care versus Placebo plus Standard of Care in Adult Subjects with Active Lupus Nephritis
  • TULIP- A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Phase 3 Study Evaluating the Efficacy and Safety of Anifrolumab in Adult Subjects with Active Systemic Lupus Erythematosus
  • Vectra- Prospective Outcomes Study: Vectra DA Guided Care Compared to Usual Care
  • AbbVie M14-465: A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 to Placebo and to Adalimumab in Subjects with Moderately to Severely Active Rheumatoid Arthritis Who are on Stable Background of Methotrexate (MTX) and Who Have an Inadequate Response to MTX (MTX-IR)

Surgery Clinic

  • Linx PAS: A Post-Approval Study of the LINX Reflux Management System (Closed to enrollment)
  • AAA: Zenith® Low Profile AAA Endovascular Graft Clinical Study (closed to enrollment)
  • Caliber: Randomized Controlled Trial of LINX versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease

If you are interested in getting additional information on a research study, please contact:

Jonean Thorsen, RN, CRC
(608) 775-2651 or (800) 362-9567, ext. 52651

Christine Roraff, RN, CRC
(608) 775-3474 or (800) 362-9567, ext. 53474

Nikki Frahm-Ward, RN
(608) 775-2894 or (800) 362-9567, ext. 52894

Industry Sponsored Research

Clinical research at Gundersen vital to FDA approval process

For several years, Gundersen Health System has joined with other major medical centers to conduct research trials essential in determining the safety and effectiveness of new medicines and technologies. Many Gundersen departments have participated in these trials—among them Cardiology, Endocrinology, Family Practice, Internal Medicine, Neurology, Pediatrics, Pulmonary, Rheumatology and Urology.

The Clinical Research department is self-supporting. All or most clinical trial-related costs such as clinic visits, laboratory tests, study drugs or devices and patient stipends for time and travel expenses are paid for with funds provided by the sponsoring pharmaceutical or medical device companies.

All patient participation in clinical trials is voluntary. Some patients volunteer hoping to benefit from a promising new medication or treatment that is not yet approved by the Food and Drug Administration. Most patients also are motivated by a desire to help others by providing information that could increase understanding and lead to better treatments.

Love + Medicine

Every day, Gundersen Health System delivers great medicine plus a little something extra—we call it Love + Medicine.

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